Set in rural Louisiana, True Blood follows the world of vampires, who have just recently "come out of the coffin". For the first time in history, a Japanese-manufactured synthetic blood allows vampires to co-exist peacefully with humans, but the question remains…will they? The series centers around Sookie Stackhouse (Academy Award and Golden Globe winner Anna Paquin, Piano, True Blood), a telepathic waitress who winds up falling for vampire Bill Compton (Stephen Moyer, The Starter Wife).